0

Your Cart is Empty

References

  1. Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review. Timur Liwinski et al. Nutrients. 2023. Click here
  2. Higher vitamin B6 intake is associated with lower depression and anxiety risk. Marzi Kafeshani et al. Vitamin and Nutrition Research. 2019.  Click here 
  3. Vitamin levels in adults with ADHD. Elisabeth Toverud Landaas et al. BJPsych Open. 2018. Click here
  4. Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels. Tanja Lukovac et al. Children. 2024.  Click here 
  5. High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Tucker Katherine L et al. The American Journal of Clinical Nutrition 2005. Click here
  6. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment. Shazia Jatoi et al. Cureus. 2020. Click here
  7. The Association Between Folate and Alzheimer's Disease: A Systematic Review an. Xiaohong Zhang et al. Front Neurosci. 2021. Click here 
  8. Folic acid, ageing, depression, and dementia - PMC. E H Reynolds. BMJ. 2002. Click here
  9. Protein N-homocysteinylation: From cellular toxicity to neurodegeneration - Sc. Gurumayum Suraj Sharma et al. Biochimica et Biophysica Acta (BBA) - General Subjects. 2015. Click here
  10. The Cerebrospinal Fluid Concentration of Methyltetrahydrofolate and Serum Folate in Children with Developmental Delay, Regression, and/or Refractory Epilepsy. Nemati et al. Neurology India. 2021. Click here
  11. Biomarkers of folate and vitamin B12 status in cerebrospinal fluid. Wolfgang Herrmann et al. Clinical Chemistry and Laboratory Medicine (CCLM). 2007. Click here
  12. Homocysteine, folate and vitamin B12 in neuropsychiatric diseases: review and treatment recommendations. Olaf Stanger et al. Zurich Open Repository and Archive. 2009. Click here
  13. The Association Between Folate and Alzheimer's Disease: A Systematic Review and Meta-Analysis. Xiaohong Zhang et al. Front. Neurosci. 2021. Click here
  14. Homocysteinylation of neuronal proteins contributes to folate deficiency‐assoc. Nassila Akchiche et al. The FASEB Journal Volume 26, Issue 10. 2012. Click here 
  15. Mutations in cystathionine β‐synthase or methylenetetrahydrofolate reductase g. Hieronim Jakubowski et al. The FASEB Journal Volume 22, Issue 12. 2008. Click here
  16. Folate deprivation induces neurodegeneration: roles of oxidative stress and in. Pei I Ho et al. Neurobiology of disease. 2003. Click here
  17. Folate deficiency-induced oxidative stress and apoptosis are mediated via homo. C.-L Chern et al. Biomedicine & Pharmacotherapy Volume 55, Issue 8. 2001. Click here
  18. Folate deprivation induced neuroinflammation impairs cognition. Afridi Shaikh et al. Neuroscience Letters. 2023. Click here
  19. Frontiers | Folate Reverses NF-κB p65/Rela/IL-6 Level Induced by Hyperhomocyst. Lihua Zhang et al. Sec. Inflammation Pharmacology Volume 12. 2021. Click here
  20. Impact of supplementation with vitamins B6, B12, and/or folic acid on the reduction of homocysteine levels in patients with mild cognitive impairment: A systematic review. Gloria Olaso-Gonzalez et al. Special Issue:Biological responses to stressors. 2021. Click here
  21. Effects of folic acid supplementation on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials - ScienceDirect. S. Fatahi b et al. Nutrition, Metabolism and Cardiovascular Diseases Volume 29, Issue 5. 2019. Click here
  22. Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial - PubMed. Jéssica Vanessa de Carvalho Lisboa et al. Randomized Controlled Trial Nutrients. 2020. Click here
  23. Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial. A. David Smith et al. PLoS ONE. 2010. Click here
  24. Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment. - Abstract - Europe PMC. Lehmann M et al. Dementia and Geriatric Cognitive Disorders. 2003. Click here
  25. Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI | Scientific Reports. Fei Ma et al. Scientific Reports. 2016. Click here
  26. Folate supplementation as a beneficial add‐on treatment in relieving depressive symptoms: A meta‐analysis of meta‐analyses. Shan Gao et al. Food Science & Nutrition. 2024.  Click here
  27. The importance of thiamine (vitamin B1) in humans. Małgorzata Mrowicka et al. Bioscience Reports. 2023. Click here
  28. The effect of riboflavin supplementation on the systemic redox status in healthy volunteers: A post-hoc analysis of the RIBOGUT trial. Arno R. Bourgonje et al. Free Radical Biology and Medicine. 2022. Click here
  29. Vitamin B3 Provides Neuroprotection via Antioxidative Stress in a Rat Model of Anterior Ischemic Optic Neuropathy. Tu-Wen Chen et al. Antioxidants (Basel). 2022. Click here
  30. Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation. Qinyu Ma et al. Am J Transl Res. 2019. Click here
  31. Full article: Role of vitamin B6 status on antioxidant defenses, glutathione, and related enzyme activities in mice with homocysteine-induced oxidative stress. Cheng-Chin Hsu et al. Food & Nutrition Research. 2014. Click here
  32. Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore. Bashir M Rezk et al. FEBS Letters. 2003. Click here
  33. Vitamin B12 in Relation to Oxidative Stress: A Systematic Review. Erik E. van de Lagemaat. Nutrients. 2019. Click here
  34. The Antioxidant Properties of Zinc. Powell Saul R. The Journal of Nutrition. 2000. Click here
  35. Emerging role of selenium in treatment of rheumatoid arthritis: An insight on its antioxidant properties. Naila Qamar. Journal of Trace Elements in Medicine and Biology. 2021. Click here
  36. Effect of Riboflavin Status on the Homocysteine-lowering Effect of Folate in Relation to the MTHFR (C677T) Genotype. Stuart J Moat et al. Clinical Chemistry. 2003. Click here
  37. Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete. Michelle C McKinley et al. The American Journal of Clinical Nutrition. 2001. Click here
  38. Homocysteine Lowering by Folate-Rich Diet or Pharmacological Supplementations in Subjects with Moderate Hyperhomocysteinemia. Bruno Zappacosta. Nutrients. 2013. Click here
  39. Efficacy of Methylcobalamin to Normalise Elevated Homocysteine of Vitamin B12 Deficient Vegetarians: A Double Blind Placebo Control Study. D. Obersby. Emerging Sources Citation Index (ESCI). 2023. Click here
  40. Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B12, and folate in a postmenopausal population. Héctor Vázquez-Lorente et al. Journal of Trace Elements in Medicine and Biology. 2022. Click here
  41. Serum selenium is associated with plasma homocysteine concentrations in elderly humans. Sonia González et al. J Nutr. 2004.  Click here
  42. Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial. Ali Ghaleiha et al. Eur Arch Psychiatry Clin Neurosci. 2016. Click here
  43. Mental Health Component Scale Is Positively Associated with Riboflavin Intake in People with Central Obesity. Charalampia Amerikanou et al. Nutrients. 2023. Click here
  44. Vitamin B6: A new approach to lowering anxiety, and depression? Durrani et al. Annals of Medicine and Surgery. 2022. Click here
  45. Folate in Depression: Efficacy, Safety, Differences in Formulations, and Clinical Issues. Maurizio Fava et al. J Clin Psychiatry. 2009. Click here
  46. The effects of vitamin B on the immune/cytokine network and their involvement in depression. Kathleen Mikkelsen et al. Maturitas. 2017. Click here
  47. The efficacy of zinc supplementation in depression: Systematic review of randomised controlled trials. Jun Lai et al. Journal of Affective Disorders. 2012. Click here
  48. The role of selenium in depression: a systematic review and meta-analysis of human observational and interventional studies. Sana Sadat Sajjadi et al. Scientific Reports. 2022. Click here
  49. The effects of vitamin B on the immune/cytokine network and their involvement in depression. Kathleen Mikkelsen et al. Maturitas. 2017. Click here
  50. Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial. Ali Ghaleiha et al. Eur Arch Psychiatry Clin Neurosci. 2016. Click here
  51. Folate supplementation as a beneficial add‐on treatment in relieving depressive symptoms: A meta‐analysis of meta‐analyses. Shan Gao et al. Food Science & Nutrition - Wiley Online Library. 2024. Click here
  52. Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depression. Prerna Sangle et al. Cureus. 2020. Click here
  53. Effects of Zinc Supplementation in Patients with Major Depression: A Randomized Clinical Trial. Elham Ranjbar et al. Iran J Psychiatry. 2013. Click here
  54. Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial. Ehsan Ullah Syed et al. Open Neurol J. 2013. Click here
  55. Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry. H Fanet et al. Curr Neuropharmacol. 2021. Click here
  56. Consensus guideline for the diagnosis and treatment of tetrahydrobiopterin (BH4) deficiencies. Thomas Opladen et al. Orphanet Journal of Rare Diseases 15, Article number: 126. 2020. Click here
  57. S-Adenosyl Methionine - an overview. Cory Szybala ND et al. Foot and Ankle Clinics. 2008. Click here
  58. High‑dose folic acid improves endothelial function by increasing tetrahydrobiopterin and decreasing homocysteine levels. Min Zhang et al. Molecular Medicine Reports Volume 10. 2014. Click here
  59. Folate in Depression: Efficacy, Safety, Differences in Formulations, and Clinical Issues. Maurizio Fava et al. J Clin Psychiatry. 2009. Click here
  60. Folate supplementation as a beneficial add-on treatment in relieving depressive symptoms: A meta-analysis of meta-analyses. Shan Gao et al. Food Sci Nutr. 2024. Click here

Subscribe