Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review. Timur Liwinski et al. Nutrients. 2023.Click here
Higher vitamin B6 intake is associated with lower depression and anxiety risk. Marzi Kafeshani et al. Vitamin and Nutrition Research. 2019. Click here
Vitamin levels in adults with ADHD. Elisabeth Toverud Landaas et al. BJPsych Open. 2018. Click here
Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels. Tanja Lukovac et al. Children. 2024. Click here
High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Tucker Katherine L et al. The American Journal of Clinical Nutrition 2005. Click here
Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment. Shazia Jatoi et al. Cureus. 2020. Click here
The Association Between Folate and Alzheimer's Disease: A Systematic Review an. Xiaohong Zhang et al. Front Neurosci. 2021. Click here
Folic acid, ageing, depression, and dementia - PMC. E H Reynolds. BMJ. 2002. Click here
Protein N-homocysteinylation: From cellular toxicity to neurodegeneration - Sc. Gurumayum Suraj Sharma et al. Biochimica et Biophysica Acta (BBA) - General Subjects. 2015. Click here
The Cerebrospinal Fluid Concentration of Methyltetrahydrofolate and Serum Folate in Children with Developmental Delay, Regression, and/or Refractory Epilepsy. Nemati et al. Neurology India. 2021.Click here
Biomarkers of folate and vitamin B12 status in cerebrospinal fluid. Wolfgang Herrmann et al. Clinical Chemistry and Laboratory Medicine (CCLM). 2007.Click here
Homocysteine, folate and vitamin B12 in neuropsychiatric diseases: review and treatment recommendations. Olaf Stanger et al. Zurich Open Repository and Archive. 2009.Click here
The Association Between Folate and Alzheimer's Disease: A Systematic Review and Meta-Analysis. Xiaohong Zhang et al. Front. Neurosci. 2021.Click here
Homocysteinylation of neuronal proteins contributes to folate deficiency‐assoc. Nassila Akchiche et al. The FASEB Journal Volume 26, Issue 10. 2012. Click here
Mutations in cystathionine β‐synthase or methylenetetrahydrofolate reductase g. Hieronim Jakubowski et al. The FASEB Journal Volume 22, Issue 12. 2008. Click here
Folate deprivation induces neurodegeneration: roles of oxidative stress and in. Pei I Ho et al. Neurobiology of disease. 2003.Click here
Folate deficiency-induced oxidative stress and apoptosis are mediated via homo. C.-L Chern et al. Biomedicine & Pharmacotherapy Volume 55, Issue 8. 2001. Click here
Folate deprivation induced neuroinflammation impairs cognition. Afridi Shaikh et al. Neuroscience Letters. 2023. Click here
Frontiers | Folate Reverses NF-κB p65/Rela/IL-6 Level Induced by Hyperhomocyst. Lihua Zhang et al. Sec. Inflammation Pharmacology Volume 12. 2021. Click here
Impact of supplementation with vitamins B6, B12, and/or folic acid on the reduction of homocysteine levels in patients with mild cognitive impairment: A systematic review. Gloria Olaso-Gonzalez et al. Special Issue:Biological responses to stressors. 2021. Click here
Effects of folic acid supplementation on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials - ScienceDirect. S. Fatahi b et al. Nutrition, Metabolism and Cardiovascular Diseases Volume 29, Issue 5. 2019. Click here
Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial - PubMed. Jéssica Vanessa de Carvalho Lisboa et al. Randomized Controlled Trial Nutrients. 2020. Click here
Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: A Randomized Controlled Trial. A. David Smith et al. PLoS ONE. 2010. Click here
Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment. - Abstract - Europe PMC. Lehmann M et al. Dementia and Geriatric Cognitive Disorders. 2003. Click here
Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI | Scientific Reports. Fei Ma et al. Scientific Reports. 2016. Click here
Folate supplementation as a beneficial add‐on treatment in relieving depressive symptoms: A meta‐analysis of meta‐analyses. Shan Gao et al. Food Science & Nutrition. 2024. Click here
The importance of thiamine (vitamin B1) in humans. Małgorzata Mrowicka et al. Bioscience Reports. 2023. Click here
The effect of riboflavin supplementation on the systemic redox status in healthy volunteers: A post-hoc analysis of the RIBOGUT trial. Arno R. Bourgonje et al. Free Radical Biology and Medicine. 2022. Click here
Vitamin B3 Provides Neuroprotection via Antioxidative Stress in a Rat Model of Anterior Ischemic Optic Neuropathy. Tu-Wen Chen et al. Antioxidants (Basel). 2022. Click here
Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation. Qinyu Ma et al. Am J Transl Res. 2019. Click here
Full article: Role of vitamin B6 status on antioxidant defenses, glutathione, and related enzyme activities in mice with homocysteine-induced oxidative stress. Cheng-Chin Hsu et al. Food & Nutrition Research. 2014. Click here
Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore. Bashir M Rezk et al. FEBS Letters. 2003. Click here
Vitamin B12 in Relation to Oxidative Stress: A Systematic Review. Erik E. van de Lagemaat. Nutrients. 2019. Click here
The Antioxidant Properties of Zinc. Powell Saul R. The Journal of Nutrition. 2000. Click here
Emerging role of selenium in treatment of rheumatoid arthritis: An insight on its antioxidant properties. Naila Qamar. Journal of Trace Elements in Medicine and Biology. 2021. Click here
Effect of Riboflavin Status on the Homocysteine-lowering Effect of Folate in Relation to the MTHFR (C677T) Genotype. Stuart J Moat et al. Clinical Chemistry. 2003. Click here
Low-dose vitamin B-6 effectively lowers fasting plasma homocysteine in healthy elderly persons who are folate and riboflavin replete. Michelle C McKinley et al. The American Journal of Clinical Nutrition. 2001. Click here
Homocysteine Lowering by Folate-Rich Diet or Pharmacological Supplementations in Subjects with Moderate Hyperhomocysteinemia. Bruno Zappacosta. Nutrients. 2013. Click here
Efficacy of Methylcobalamin to Normalise Elevated Homocysteine of Vitamin B12 Deficient Vegetarians: A Double Blind Placebo Control Study. D. Obersby. Emerging Sources Citation Index (ESCI). 2023. Click here
Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B12, and folate in a postmenopausal population. Héctor Vázquez-Lorente et al. Journal of Trace Elements in Medicine and Biology. 2022. Click here
Serum selenium is associated with plasma homocysteine concentrations in elderly humans. Sonia González et al. J Nutr. 2004. Click here
Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial. Ali Ghaleiha et al. Eur Arch Psychiatry Clin Neurosci. 2016. Click here
Mental Health Component Scale Is Positively Associated with Riboflavin Intake in People with Central Obesity. Charalampia Amerikanou et al. Nutrients. 2023. Click here
Vitamin B6: A new approach to lowering anxiety, and depression? Durrani et al. Annals of Medicine and Surgery. 2022. Click here
Folate in Depression: Efficacy, Safety, Differences in Formulations, and Clinical Issues. Maurizio Fava et al. J Clin Psychiatry. 2009. Click here
The effects of vitamin B on the immune/cytokine network and their involvement in depression. Kathleen Mikkelsen et al. Maturitas. 2017. Click here
The efficacy of zinc supplementation in depression: Systematic review of randomised controlled trials. Jun Lai et al. Journal of Affective Disorders. 2012. Click here
The role of selenium in depression: a systematic review and meta-analysis of human observational and interventional studies. Sana Sadat Sajjadi et al. Scientific Reports. 2022. Click here
The effects of vitamin B on the immune/cytokine network and their involvement in depression. Kathleen Mikkelsen et al. Maturitas. 2017.Click here
Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial. Ali Ghaleiha et al. Eur Arch Psychiatry Clin Neurosci. 2016. Click here
Folate supplementation as a beneficial add‐on treatment in relieving depressive symptoms: A meta‐analysis of meta‐analyses. Shan Gao et al. Food Science & Nutrition - Wiley Online Library. 2024. Click here
Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depression. Prerna Sangle et al. Cureus. 2020. Click here
Effects of Zinc Supplementation in Patients with Major Depression: A Randomized Clinical Trial. Elham Ranjbar et al. Iran J Psychiatry. 2013. Click here
Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial. Ehsan Ullah Syed et al. Open Neurol J. 2013.Click here
Tetrahydrobioterin (BH4) Pathway: From Metabolism to Neuropsychiatry. H Fanet et al. Curr Neuropharmacol. 2021. Click here
Consensus guideline for the diagnosis and treatment of tetrahydrobiopterin (BH4) deficiencies. Thomas Opladen et al. Orphanet Journal of Rare Diseases 15, Article number: 126. 2020.Click here
S-Adenosyl Methionine - an overview. Cory Szybala ND et al. Foot and Ankle Clinics. 2008.Click here
High‑dose folic acid improves endothelial function by increasing tetrahydrobiopterin and decreasing homocysteine levels. Min Zhang et al. Molecular Medicine Reports Volume 10. 2014. Click here
Folate in Depression: Efficacy, Safety, Differences in Formulations, and Clinical Issues. Maurizio Fava et al. J Clin Psychiatry. 2009.Click here
Folate supplementation as a beneficial add-on treatment in relieving depressive symptoms: A meta-analysis of meta-analyses. Shan Gao et al. Food Sci Nutr. 2024.Click here
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